Why Estrogen Dominance is NOT the cause of your infertility

Infertility is a deeply personal and often challenging journey for many individuals and couples. As they navigate this path, it's common to seek answers and explanations for your struggles. One concept that has frequently emerged in discussions about infertility, especially online is "estrogen dominance." While it's true that elevated estrogen levels can be observed in certain patients, like those with hormonal disorders or higher BMIs, it's essential to understand that estrogen dominance is not the root cause of infertility and is not a true medical diagnosis. In today’s blog, we will explore why this commonly held belief may not hold true and what you really need to know along your infertility journey. 

Estrogen: A Key Player in Reproductive Health

Estrogen often gets a bad rap, especially on social media but did you know estrogen is VITAL for your fertility. It plays a pivotal role in regulating the menstrual cycle, ensuring proper development of the uterine lining, and supporting the overall health of the ovaries. It's also involved in the maturation of eggs and the successful implantation of a fertilized embryo.

Estrogen Dominance: A Misunderstood Term

Estrogen dominance is a term often used to describe a hormonal imbalance where estrogen levels are perceived to be too high in relation to other hormones like progesterone. While it's true that hormonal imbalances can contribute to fertility issues, the concept of estrogen dominance can be misleading.

Understanding the Complexity of Hormonal Imbalances

Infertility is a complex condition with multiple potential causes. The human body operates within a delicate hormonal balance, and many factors can disrupt this equilibrium. High estrogen levels may be one piece of the puzzle, but they are rarely the sole culprit behind infertility. Infact, we have absolutely no data or evidence to date to prove that elevated estrogen is the cause of infertility. Instead, it's essential to consider a broader range of factors, such as:

  1. Ovulatory Disorders: Infertility is often linked to issues with ovulation, which can be influenced by a variety of factors, including polycystic ovary syndrome (PCOS) and hypothalamic dysfunction.
  2. Male Factor Infertility: Infertility can result from male factors as well, such as low sperm count or poor sperm quality.
  3. Tubal Factors: Blockages or damage to the fallopian tubes can prevent the egg and sperm from meeting, leading to infertility.
  4. Uterine Abnormalities: Structural issues within the uterus can hinder implantation or the development of a healthy pregnancy.
  5. Age: As women age, the quality and quantity of eggs naturally decline, impacting fertility.
  6. Lifestyle Factors: Diet, exercise, stress levels, nutrient deficiencies, and other lifestyle factors can also play significant roles in fertility.
  7. Other underlying conditions: autoimmune, clotting, metabolic disorders. 

The Role of Estrogen in Infertility

While it's true that some individuals, particularly those with hormonal disorders or higher body mass indexes (BMIs), may have elevated estrogen levels when testing serum estradiol levels, it's important to note that correlation does not imply causation. Elevated estrogen alone does not necessarily lead to infertility. It's often part of a more complex hormonal picture.

Medical Evidence

Numerous studies and medical experts support the notion that estrogen dominance is an oversimplified and misleading concept when it comes to infertility causation. A 2017 review in the journal "Fertility and Sterility" concluded that high estrogen levels, while present in some infertile individuals, should not be regarded as the primary cause of infertility without considering other contributing factors. In other words, if you are being told you have estrogen dominance and it is the cause of your infertility, we are oversimplifying a complex system which in turn can lead to delays in adequate testing and treatment options. 

Infertility is a multifaceted issue that requires a comprehensive evaluation of various factors. While elevated estrogen levels can be observed in certain patient populations, it's crucial to avoid oversimplifying the problem by attributing infertility solely to estrogen dominance. Seeking expert medical advice and thorough evaluation is the best approach to understanding and addressing the complex causes of infertility. Remember, infertility is a challenge, but it is often treatable, and hope remains for those on their journey to motherhood.


About the Author: Meet Dr. ZenAlissia Zenhausern- Pfeiffer, NMD, FABNE, (commonly known by her patients as Dr. Zen), is a licensed naturopathic doctor board certified in naturopathic endocrinology and the founder of NMD Wellness of Scottsdale, a premier naturopathic medical practice that focuses on helping women to take a proactive approach to their hormone and fertility health. Dr. Zen has been featured as a lead expert in Forbes, Shape Magazine, and Instyle and is deeply passionate about bridging the gap between traditional and natural medicine in the world of fertility. She works with a variety of hormone related issues including PCOS, endometriosis and unexplained infertility. Her goal is to help more women get back into the driver’s seat of their own health to make lasting transformational changes to their health to bring more cute and adorable babies into this world. Read More About Dr. Zen...